A high dosage of extra intramuscular corticosteroids can result in almost-complete disappearance of eosinophilic cells leading to reduced use of “rescue” medications apart from facilitating improvements in lung function tests of patients. This finding was revealed by investigators during a study of patients with severe asthma having eosinophils in their sputum despite extensive antiasthma medication.
Eosinophils are a type of white blood cell that constitute around 1-3 percent of the total white cell count in the body. When infectious cells or foreign substances enter the body, lymphocytes and neutrophils attract eosinophils that release toxic substances to destroy abnormal cells.
The authors note that injected corticosteroids can reach the region of bone marrow besides minimizing eosinophils being produced by processes involving inflamed tissue.
